Avian Influenza Virus Ab Rapid Test kit | |
Chidule | Kuzindikira kwa Antibody yeniyeni ya Avian Influenzamkati mwa mphindi 15 |
Mfundo yofunika | Gawo limodzi la immunochromatographic assay |
Zolinga Zozindikira | Avian Influenza Antibody |
Chitsanzo | Seramu |
Nthawi yowerenga | 10-15 mphindi |
Kuchuluka | 1 bokosi (zida) = 10 zida (payekha payokha) |
Zamkatimu | Zida zoyesera, mabotolo a Buffer, zotsitsa zotaya, ndi ma swabs a Thonje |
Chenjezo | Gwiritsani ntchito mkati mwa mphindi 10 mutatsegulaGwiritsani ntchito mlingo woyenera (0.1 ml wa dropper)Gwiritsani ntchito pambuyo pa mphindi 15-30 ku RT ngati zasungidwa m'malo oziziraGanizirani zotsatira za mayeso ngati zosavomerezeka pakatha mphindi 10 |
Chimfine cha Avian, chomwe chimadziwika kuti ndi chimfine kapena chimfine cha mbalame, ndi chimfine chamitundumitundu chomwe chimayambitsidwa ndi ma virus omwe amatengera mbalame.Mtundu womwe uli pachiwopsezo chachikulu kwambiri ndi chimfine cha avian (HPAI).Chimfine cha mbalame ndi chofanana ndi chimfine cha nkhumba, chimfine cha galu, chimfine cha kavalo ndi chimfine cha anthu monga matenda omwe amayamba chifukwa cha tizilombo toyambitsa matenda a chimfine omwe asintha kuti akhale ndi gulu linalake.Mwa mitundu itatu ya mavairasi a chimfine (A, B, ndi C), kachilombo ka fuluwenza A ndi matenda a zoonotic okhala ndi malo achilengedwe pafupifupi mbalame zonse.Avian influenza, pazifukwa zambiri, amatanthauza kachilombo ka fuluwenza A.
Ngakhale chimfine A chimasinthidwa kukhala mbalame, chimathanso kusintha mosasunthika ndikupititsa patsogolo kufalikira kwa munthu ndi munthu.Kafukufuku waposachedwa wa chimfine pa majini a kachilombo ka chimfine cha ku Spain akuwonetsa kuti ili ndi majini otengera mtundu wa anthu ndi mbalame.Nkhumba zimatha kutenga kachilombo ka fuluwenza ya anthu, avian, ndi nkhumba, zomwe zimapangitsa kuti ma jini osakanikirana (reassortment) apange kachilombo katsopano, komwe kungayambitse kusintha kwa antigenic kupita ku kachilombo ka fuluwenza A komwe anthu ambiri alibe chitetezo chokwanira. chitetezo motsutsana.
Mitundu ya chimfine ya Avian imagawidwa m'mitundu iwiri kutengera momwe amapangira: high pathogenicity (HP) kapena low pathogenicity (LP).Mitundu yodziwika bwino ya HPAI, H5N1, idasiyanitsidwa koyamba ndi tsekwe wolimidwa m'chigawo cha Guangdong, China mu 1996, ndipo ilinso ndi mitundu yotsika ya tizilombo toyambitsa matenda yomwe imapezeka ku North America.[8][9]Mbalame zomwe zili m'ndende sizingatenge kachilomboka ndipo sipanakhalepo lipoti loti pali mbalame ina yomwe ili ndi fuluwenza kuyambira 2003. Nkhunda zimatha kutenga tizilombo toyambitsa matenda, koma nthawi zambiri zimadwala ndipo sizingathe kufalitsa kachilomboka bwino kwa anthu kapena nyama zina.
Pali mitundu ingapo ya mavairasi a chimfine cha avian, koma mitundu ina yokha ya mitundu isanu yomwe imadziwika kuti imakhudza anthu: H5N1, H7N3, H7N7, H7N9, ndi H9N2.Pafupifupi munthu m'modzi, mayi wachikulire m'chigawo cha Jiangxi, China, adamwalira ndi chibayo mu Disembala 2013 kuchokera ku mtundu wa H10N8.Iye anali munthu woyamba kufa chifukwa cha vuto limeneli.
Nthawi zambiri anthu amadwala chimfine cha avian chimachitika chifukwa chogwira mbalame zomwe zafa kapena kukhudzana ndi madzi omwe ali ndi kachilomboka.Angathenso kufalikira kudzera pamalo oipitsidwa ndi zitosi.Ngakhale mbalame zambiri zakutchire zimakhala ndi mtundu wochepa chabe wa mtundu wa H5N1, mbalame zoweta ngati nkhuku kapena turkeys zikadwala, H5N1 ikhoza kukhala yakupha kwambiri chifukwa mbalame nthawi zambiri zimakhala pafupi.H5N1 ndi chiwopsezo chachikulu ku Asia ndi nkhuku zomwe zili ndi kachilombo chifukwa cha ukhondo komanso malo oyandikira.Ngakhale kuti n’zosavuta kuti anthu atenge matendawa kuchokera ku mbalame, kupatsirana kwa munthu ndi munthu kumakhala kovuta kwambiri popanda kukhudzana kwa nthawi yaitali.Komabe, akuluakulu azaumoyo ali ndi nkhawa kuti mitundu ya chimfine ya avian imatha kusinthika kuti isapatsirane mosavuta pakati pa anthu.
Kufalikira kwa H5N1 kuchokera ku Asia kupita ku Europe ndikotheka chifukwa cha malonda a nkhuku ovomerezeka komanso osaloledwa kuposa kufalikira kudzera mkusamuka kwa mbalame zakuthengo, popeza kuti m'maphunziro aposachedwa, ku Asia kunalibe kukwera kwachiwiri kwa matenda pamene mbalame zakuthengo zimasamukanso kumwera kuchokera pakuweta. maziko.M'malo mwake, machitidwe amatendawa adatsata mayendedwe monga njanji, misewu, ndi malire amayiko, zomwe zikuwonetsa kuti malonda a nkhuku ndi otheka kwambiri.Ngakhale kuti ku United States kwakhala mitundu yambiri ya chimfine cha avian, chazimitsidwa ndipo sichinadziwike kuti chingapatsire anthu.
HA subtype | NA subtype | Avian influenza A virus |
H1 | N1 | A/bakha/Alberta/35/76(H1N1) |
H1 | N8 | A/bakha/Alberta/97/77(H1N8) |
H2 | N9 | A/bakha/Germany/1/72(H2N9) |
H3 | N8 | A/bakha/Ukraine/63(H3N8) |
H3 | N8 | A/bakha/England/62(H3N8) |
H3 | N2 | A/turkey/England/69(H3N2) |
H4 | N6 | A/bakha/Czechoslovakia/56(H4N6) |
H4 | N3 | A/bakha/Alberta/300/77(H4N3) |
H5 | N3 | A/tern/South Africa/300/77(H4N3) |
H5 | N4 | A/Ethiopia/300/77(H6N6) |
H5 | N6 | H5N6 |
H5 | N8 | Mtengo wa H5N8 |
H5 | N9 | A/turkey/Ontario/7732/66(H5N9) |
H5 | N1 | A/chick/Scotland/59(H5N1) |
H6 | N2 | A/turkey/Massachusetts/3740/65(H6N2) |
H6 | N8 | A/turkey/Canada/63(H6N8) |
H6 | N5 | A/shearwater/Australia/72(H6N5) |
H6 | N1 | A/bakha/Germany/1868/68(H6N1) |
H7 | N7 | A/fowl mliri virus/Dutch/27(H7N7) |
H7 | N1 | A/chick/Brescia/1902(H7N1) |
H7 | N9 | A/chick/China/2013(H7N9) |
H7 | N3 | A/turkey/England/639H7N3) |
H7 | N1 | A/fowl mliri virus/Rostock/34(H7N1) |
H8 | N4 | A/turkey/Ontario/6118/68(H8N4) |
H9 | N2 | A/turkey/Wisconsin/1/66(H9N2) |
H9 | N6 | A/bakha/Hong Kong/147/77(H9N6) |
H9 | N7 | A/turkey/Scotland/70(H9N7) |
H10 | N8 | A/zinziri/Italy/1117/65(H10N8) |
H11 | N6 | A/bakha/England/56(H11N6) |
H11 | N9 | A/bakha/Memphis/546/74(H11N9) |
H12 | N5 | A/bakha/Alberta/60/76/(H12N5) |
H13 | N6 | A/gull/Maryland/704/77(H13N6) |
H14 | N4 | A/bakha/Gurjev/263/83(H14N4) |
H15 | N9 | A/shearwater/Australia/2576/83(H15N9) |